Originally used in an episode of Family Guy in the end of their 1999 season, by cardinals reading through the bible. Later used by the Simpsons' Homer when he became a missionary. Now, it's just slang for anything from Jesus to shrooms.
SL'r: "My brother must of disconnected after it was done"
Jebus: "You and your Brother can enjoy Public Purgatory, while felating each other in the back seat of the Short Bus"