Yotsuba

The Fourth Nakano sister from the anime called Quintessential Quintuplets. She's definitely the best girl and she loves smiling always.

Yotsuba really deserves as a bride

by NotYotsuba October 21, 2021

yotsss

The Yiddish Word for "Jerk."

Hax00r: HAHAHAHA!!! I Pwned You Again!!!
N00b: Screw Off You Yotsss!

by Esleox June 10, 2005

yousof

the king of memes, attractive, and every guy wants to be his friend due to his amazing attitude

yousof is my homie

by khiyara bin tamatim December 8, 2018

YOTO

You're Only Tough Online

so stop being a pussy and talking shit about them behind your computer screen #YOTO

by young average joe August 16, 2012

YOSO

Your Only Squirt Once

I screamed YOSO while I jerked off in my girl's hair while she was sleeping.

by FabledPoet October 24, 2012

yoso

You Only Stick Once. The process of hitting on multiple people knowing that you will at least hook up with one of them. The genesis of this acronym comes from the expression, "Throw enough shit against the wall and something is bound to stick."

I just tinder messaged 50 girls. At least one of them is going to be down. #yoso

by aro8888 August 20, 2014

Yotobi

an italian youtuber, he does a video every 40 years but everyone likes him always.
he isn't hitler
he is something more than that

Yotobi is the new hitler

by Sinister⛧ #0666 November 18, 2020