buttslut Share definition Flag basicaly, a slut, who either lives in a butt, or likes up the butt. can refer to homesexuals. related to slut and skank A. Yeah, that buttslut smells like arse. Probably because she lives in one. B. Damn, bitch, you like it up the rear, just like my old buttslut. C. Buttslut is another cool word for skank. :O buttslut by kiwiskill April 17, 2006 Get the buttslut mug.