Tweak

To not relax; to not chill; to mimic someone suffering from a unique combination of schizophrenia and terets, presenting a lack of logical thought upon speaking.

Don't tweak bro, relax.

I'm chill man, I never tweak on acid.

Relax for a second, or you might start to tweak.

by TweakOrBust December 5, 2017

Tweak

To stimulate a female's clitoris to the point of a micro-orgasm.

To the theme song tune of 'Kim Possible'. Call me beep me if you wanna tweak me.

by Kimfuckable May 3, 2019

Tweak

A guy who talks shit behind peoples back but is coward in front of the person and is too fat to be called a Twink. He makes fun of and points out insecurities and he’s more insecure of himself. Victimizes himself because he’s a wimp to say that he’s wrong. He is an instigator and causes problems that aren’t that big of a deal. He also be taking jokes way too far and gets mad when you call him out and has the ugliest perm and wears emo earrings.

“Armani you fucking Tweak.”

“You Tweak ass is so annoying go somewhere else you bitch.”

“Fuck you Tweak motherfucker pussy ass bitch

by Beomtori September 21, 2023

Tweak

when you have a freak out .

When you go ape shit.

I'm gonna tweak the fuck out!

Bro, that kid fucked with me and i tweaked on him!

by pegasus12344 December 26, 2018

Tweak

A meth addict who is stuck doing pointless actions for long periods of time.

After hours of tweak activities, Theodore finally fell asleep.

by Juice Jonson May 8, 2018

Tweak

to lightly caress with the thumb and forefinger

"Tweak those nipples and spank that ass!"

by Knowerofallthings April 26, 2006

Tweak

Someone who overly acts weird, reacts in a weird way, or acts unnormal and squarish.

When a teen acts too excited in class and starts tweaking out.

by magsoldier15 January 21, 2011