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Technical Definition:

The Cellular remains of a wound when large amounts of healing has occured in an infected area, such as a skin sweat or oil duct, a epidermal blood clot, or an ingrown toenail.

Laymans terms: That yellow, slimy, goopy stuff that splatters all over the mirror when you pop a zit, or pick your scabbs, or stub your toe.
"Girls with acne are gross. I just think about all that puss on their faces!"
puss by Thomual June 13, 2004
Related Words
To be unloved, stupid, idiotic, gay, unwanted, loser, lame, Jim Wallace.
John: Get on your knee's Puss.
Jim: Ugh, OK John.
John: thats right you puss.
Puss by iJohhnyT October 29, 2010
When something is lame, dumb, annoying or stupid. Can be used as a exclamation. Various words can be added to emphasize this, like "wicked" or "double"
1. this test has 200 questions!? dude, puss.
2. Yeah, the party got canceled because the cops showed up. Wicked puss.
puss by dan the slaya May 7, 2013
used mostly in santa cruz/the valley.

a way to say how great something is.
man, this ganja is the puss

that party was puss

puss by erererererer January 24, 2008
The way a New Zealander kiwi pronounces the word piss.
Yo bra, i gotta go drink some puss and take a puss and eat some fush and chups
puss by Cammo3000 September 30, 2005