PLS 

Parking Lot Slut. Usually a girl who fucks in school parking lots in the morning.

Hey check out that PLS. Who's she with today?

PLS by BALLINNNNNNN January 21, 2009

PLS 

Post - LOST - syndrom

The feeling of loss and depression you felt after the series LOST finally ended.

All I do is sit in bed, eat a gallon of ice cream, and cry out for Jack, Sawyer, & Kate. My friends say I'm suffering from PLS.

PLS by nolaughingmatter May 30, 2010

pls 

Usually an shortened word for "please".
Used in appeals or in different context.

Thomas: "Hey Uncle Jerry, can i suck your dick pls?"
Jerry: "Sure thing Thomas! *unzips*

pls by allahisgood May 31, 2019

Pls 

The way idiots spell "please" Plz would be correct grammar. Not pls

Kat: can i pls get $10?
Lizi: *Plz, not pls.

Pls by Hang on November 25, 2015

PLS 

Pretty Little Sluts. A play off the show "Pretty Little Liars". Moslty used for making fun of it for it's slutty characters.

Dan: Yeah, my sister wouldn't give me the remote so I had to watch that stupid show pretty little liars
Tom: Oh you mean pretty little sluts, PLS?
Dan: Exactly.

PLS by gerken flocken clocken docken March 20, 2011

PLS 

Puppy Love Syndrome: usually occurs in teenagers and it is when they think that they are in love, but in reality it is just puppy love.

Dad 1: Ya i had 2 take hi in to the doctor the other day...
Dad 2: y?
Dad 1: he has a bad case of PLS..
Dad 2: o....is that like mono?
Dad 1: nope its Puppy love syndrome....
Dad 2: o shit i hope my daughter does'nt get infected too....

PLS by lolerskates2244454 June 7, 2009

PLS 

In French, "position latérale de sécurité"

or "lateral secure position." A technique used by emergency responders to orient an unconscious person so that they're slightly on their side in order to keep them from choking on their own vomit. Used often to describe being blackout drunk, whether or not you actually passed out or were put in actual PLS

Bro I went way too hard last night, ended up sloshed and in near PLS

PLS by Lesangesdelurbandictionary December 27, 2016