The Big One 

The inevitable, spectacular, and sometimes fatal accident endured by almost every motorcycle at some point in their life while riding.

Did you hear about Derek? He's in a coma, he finally had The Big One.

The Big One by NoSquidding July 28, 2020

Big One 

A devastating Earthquake that strikes the San Andreas fault line about every 100 years, last happening hitting in The 1906 San Francisco Earthquake. Most commonly used in reference to a predicted future earthquake.

I think we should invest in some sturdier infrastructure here. I mean, what about when the Big One hits?

Big One by 54229 265546437 May 28, 2018

Big Ol' Queen 

An extremely flaming gay man

Did you see Percy wearing those pink hot pants and 5 inch heels at Gay Pride? Oooeee she is such a big ol' queen!

Big Ol' Queen by ICYNDICEY December 25, 2010

The Big Onion

A less popular nickname for the United States city Chicago in Illinois

Taken from the nickname of New York, "The Big Apple"

Hey, we should take a trip up north to the Big Onion. I hear the shoreline is beautiful.

The Big Onion by My kind of town3oh!3 July 13, 2009

Big ol' weener 

A game where a man takes out his pecker and chases a woman around while saying over and over big ol' weener and if he can catch her he can fuck her.

Want to play big ol' weener?

Big ol' weener by Deep blue 2012 August 19, 2009

big one 

code for a bundle of heroin- 10 bags, otherwise known as a bun

i copped a big one for eighty in paterson and flipped it for a buck twenny to some maricóns in westchester

big one by nothing where we go January 3, 2011

the big one 

It's the one people always talk about, the mythical/legendary big one. why isn't it already defined?
Refers to anything big, a big piece of food, a big sex organ, a big butt, or anything else that is big.

Hah! He bit the big one!

the big one by wichita March 17, 2008