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Shizzle my Nizzle 

An alternative to saying "Shit" or "Dammit".
Aw, Shizzle my nizzle! I forgot my ducking purse at Starbucks!

Shizzle my Nizzle 

v. The action of causing a mass genocide, in ways not originally intended.
ex. I turned the corner and yeast began to pour from my orphans. "Shizzle my Nizzle" I said as the orphanage filled with yeast.
Shizzle my Nizzle by Doodem May 20, 2018

Shizzle My Nizzle 

saying yes or sum shit
Shizzle My Nizzle by Onb February 3, 2023

Shizzle my nizzle 

Shizzle my nizzle by fresh January 14, 2004

shizzle my nizzle 

Once upon a time there was a man called bob. Now bob liked his occasional bud, one day he ran out. Geoff happened to be with him at the time. Bob said "fo' shizzle my nizzle", Geoff ran to the local chemists and fetched Bob some more bud. Well..mary didnt like the fact that geoff went, she had longed to go to the local chemists, but never had the chance. So while Bob weren't looking she spade Geoff over the head and dragged his body 2 miles to nearest graveyard, and buried him. When Bob said "fo' shizzle my nizzle" the next day, he was expecting Geoff. There was no sign of Geoff, so he said it louder, still no sign. All of a sudden Mary came running back from the local whore house and said "ill go!!". She ran and ran and ran until....she got trampled over by en elephant. Bob never did get any more bud after that, and if you listen you can still hear his ghost shouting "fo' shizzle my nizzle".
Bob: fo' shizzle my nizzle
Geoff: (no answer)
Mary: (no answer)
shizzle my nizzle by Mr. T October 20, 2004

shizzle my nizzle 

basically means..Shit my Nigga..

all the other definitions 4 it on ere are wrong..
keisha: omg jason just got robbed!

jemal: shizzle my nizzle..lets kick yard an tell his brother