From the imortal works of Snoop Dogg, it means my nigga or the white folk in the house, my friend.
My nizzle, why you bullshitting? Roll that shit, light that shit, smoke that shit!
by chuychomp March 24, 2003
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another word for "my homie" which is another word for "my close friend"
by cheesy February 15, 2003
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A rare meaning, but it can also mean "My Nipple," rather than "My Nigger"
"Fo' shizzle, my nizzle" - For Sure, My Nipple"
by sweaterdouche February 8, 2007
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1) Snoop dog language:
My nigga
(meaning friend or associate)

2) My Nozzle
(a garden Hoze attatchment)
1) Waddup, Ma' Nizzle?

2) Ma Nizzle is sprayin' crooked, yo.
by BObo.31337.pl (its a site) August 2, 2004
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Fo' shizzle ma' nizzle" is a bastardization of "fo' sheezy mah neezy" which is a bastardization of "for sure mah nigga" which is a bastardization of "I concur with you whole-heartedly my African American brother"
yo want to get high?

for shizzle my nizzle?
by niggawhat120 January 22, 2005
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