a cramp, usually on the right hand in the area between the thumb and the index finger that is primarily caused by prolonged exposure to video game controllers
by Ivan January 23, 2004
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man #2: Yeah, I heard he's suffering from Nintenditus and hasn't used the toilet since the games release!
man #2: Yeah, I heard he's suffering from Nintenditus and hasn't used the toilet since the games release!
by Spleetbacker November 6, 2011
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Also known as Gamer's Thumb or Nintendo Thumb, Nintenditis is when some part of your thumb or wrist becomes irritated or swollen due to excessive video game playing. A person with Nintenditis will feel pain or discomfort when bending their thumbs or moving their wrists. Note that this can happen with any finger, and not just the thumb.
I concluded that I had Nintenditis when I noticed a constant pain in my thumb during a game of Super Smash Bros.
by Sm4shIsTr4sh September 5, 2016
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