1. Verb - the act of removing someone from your friends list on any social network.
1a. Verb - the act of ending a friendship with someone either on a social network or in the 3D world.

Synonym - see "unfriend"
He was tired of always inviting Dave to things and never once did Dave show up. Not to dinners, not to movies, not to free concerts, not to the clubs, nothing. Most of the time, he never even got a response, yay or nay. And Dave never invited him anywhere.

Hal was through with the whole thing and after all this time, finally, defriended the one guy he thought would be his pal forever.
by nolana plume August 25, 2009
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the act of removing a friend on your Myspace friend's list.
We broke up and he was childish enough to defriend me on Myspace.
by One who was defriended... April 7, 2006
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Defriender is a person who tries to break the friendships of other people, in a mean way. They do this because they have no friends and want people to feel their pain.
"What a Defriender. He is so mean"
by Bman111 December 1, 2016
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defriend smbd v , transitive de + friend; cf. befriend - to break off friendly relations (with smbd).

He defriended me a year after we met, with no reason or explanation. He just stopped calling, period.

I want to defriend you. Ð What's wrong? - I need something more than friendship from you. I need love.
by Mikhail Epstein November 3, 2003
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(v) To remove someone from your livejournal friends list.
"I defriend people who post quiz results. Get a life!"
by Coell May 12, 2005
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The act of deleting someone on an online socializing site like Facebook or Myspace.

This usually happens when someone you don't know requests to be your friend so you accept them to see their profile. Once you realize that you don't know them or that they are a complete creeper, you attempt to 'defriend' them. This usually proves to be a nuisance and a pain to figure out how to do.
Person 1: I'm going on this trip to France and a guy from another school friended me, I messaged him 'cause I wasn't sure who he was, and he gave me a total creeper response.

Person 2: Man, defriend that fool.
by B-RizzleforShizzle March 5, 2009
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To remove a friend from your Facebook or Myspace because you misfriended them (accidentally "friended" them or added them as a friend).
I had to defriend this dude I thought I knew from my high school days, but it turned out I didn't. He was sending me all sorts of events spam!
by Sartorialist October 21, 2008
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