F.B.S. (Fat Bitch Syndrome) 

When a heavier woman acts in ways that aren't normal or positive to garner any attention she can from others.

"Last night Bertha was starting so much drama because she wanted Rick to notice her and she wanted to keep his attention off of the better looking girls. That hooker has serious F.B.S. (Fat Bitch Syndrome)."

F.B.S. (Fat Bitch Syndrome) by brewcityboy May 1, 2012

Penis-at-12 syndrome 

A 5-alpha reductase deficiency at birth causes ambiguous to female-type external genitalia. The male has undescended testes. The deficiency essentially prevents testosterone from becoming dihydrotestosterone (DHT). Now the penis-at-12 syndrom itself occurs around puberty when the high levels of testosterone overcome the requirement of DHT...the clitoris enlarges, alas, "penis-at-12".

Damn, I'm sure glad I don't have penis-at-12 syndrome.

Penis-at-12 syndrome by eleven April 27, 2003

first piece of ass syndrome 

When a guy stays with the first girlfriend hes ever had, no matter how goddamn annoying she may be, just because he's finally getting some.

-Man eric's girlfriend is irritating as hell. Why doesn't he dump her already?
-Eh its his first girlfriend. You know, first peice of ass syndrome.

first piece of ass syndrome by Jonks January 28, 2005

First Relationship Syndrome

First Relationship Syndrome, also known as FRS, is the condition of being chronically attracted to the first person you enter a relationship with. Being inflicted with said syndrome makes the process of getting over this person when you break up all the more difficult. Common symptoms include constant distraction, sadness, and in more extreme cases, stalking.

Eddie can't get over Holly, so he's resorted to picking out of her garbage can. That pussy, it MUST be First Relationship Syndrome.

First Relationship Syndrome by Christina Monterrosa December 24, 2008

waste kyattie syndrome 

A girl/ gyal who is waste and resemble waste characteristics. This is a syndrome just as down syndrome and there is no perfect cure at the moment. The best way to get rid of a waste kyattie is to move on and talk to anther girl/gyal. The infected can be of any ethnic background, (mainly of West Indian/ Coolie decent) Many other Indain and Paki girls may suffer from this disease and share the same waste characteristics.

Yoh kevin, foget about that gyal shes a waste kyattie...

Derek Bredjin, that gurl has waste kyattie syndrome, forget bout she!

Run! There's a waste kyattie coming!

waste kyattie syndrome by The Kings Singer, MS March 14, 2010

Hunter S. Thompson Syndrome (HSTS) 

A condition characterized by the adoption, and subsequent involuntary internalization of, the mannerisms and habits of the late Hunter S. Thompson.

Johnny Depp's case of Hunter S. Thompson Syndrome (HSTS) during the filming of Fear and Loathing in Las Vegas was so accurate and deeply entrenched that it actually creeped out Thompson himself.

Hunter S. Thompson Syndrome (HSTS) by Badwig January 23, 2010

Expert Syndrome 

An ailment characterized by the need to expound on a given topic beyond actual knowledge. The advanced sufferers are often unaware of the condition, loosing the ability to distinguish opinion from fact. Unfortunately there is currently no cure for Expert Syndrome, much like Catholicism.

Did you hear Karl going on about kernel internals at lunch? He has a serious case of Expert Syndrome.

Expert Syndrome by John Kintz January 16, 2006