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sista fran 

a person that is very close to you and you love like a sister. you tell them everything and are best friends. you are almost always with each other. sista frans are BEYOND just friends
Shea: is that girl Katie your friend?
Carly: She's not only my friend, she's my sista fran

or
Katie: hey sista fran, what's up?
Carly: nothing much, wanna hang out. go shopping or something?
sista fran by runnergirl365 February 24, 2011
Related Words

pulling a fran 

Dude, where's Daniel?
He's pulling a fran.
pulling a fran by Wakantank May 16, 2008

San Fran sicko 

City that is home to degenerates, fags and other creeps
I ain't goin' to San Fran sicko where all those fags at!!!
San Fran sicko by unkkle buckk September 11, 2006

San Fran Freako 

The city of San Francisco, nicknamed so due to its large liberal extremist population.
Citizens of San Fran Freako cream their pants every time a new state legalizes gay marriage.
San Fran Freako by amplitude June 29, 2011
A man who talks and talks and talks, regardless of who is listening (or not listening). The origins of the word are derived from the word "man" and "fran drescher" (the actress who played the talkative nanny on the hit show "The Nanny".
Tom: You get your work done today ??
Bob: Hell no....man-fran popped by and wouldn't leave. He just kept talking and talking.
man-fran by manfran October 16, 2008

San Fran Sunrise 

A horrifying act of anal penetration where the partner takes a lit candle and inserts it into the recipients asshole repeatedly
Gay #1- hey I just lit a candle

Gay #2- ohhh that's so romantic

Gay #1- now i'm gonna stick it up your ass! who doesn't like a San Fran Sunrise
San Fran Sunrise by craigstand August 25, 2011