Duff

Dumb Ulgy Fat Friend. The one friend that people only talk to to find out info on their hot friends

I want to find more stuff out about Nikki. I'm going to ask her Duff

by thatonegirl3000 March 09, 2015

Duff

The cannabis material that is left after vaporization (which it is still good for cooking).

I made awesome brownies with the duff from last weeks party!

by CaraBeantown January 05, 2014

duff

Dumb Ugly Fat Friend. Every hot girl has at least one. If, in the case, that a hot girl has other hot girl friends, then they all have at least one mutual duff. Hot girls chill with them to usually make themselves seem better.

Yo dawg, we gotta get this DUFF away asap.

by the_realest_MI February 18, 2011

Duff

Designated Unpopular Fat Friend. A fat person,usually a female who is obsessed with a country boy,his friends,his momma,sister,truck and dog.

Girl: Where did all my ice cream go?
Boy: The duff must have ate it.

by brotherman94 January 21, 2012

duff

consumimg cannabis sativa by means of smoke.

wrestling is coming up soon it's about time to duff

by d-boy May 01, 2003

Duff

to spill something on your clothes.

I duffed my coffee this morning during the commute.

by Argh Dammit September 12, 2005

Duff

1.A incognito way to compliment a nice behind without being heard or looked at by the selective the female target.the term started in NJ in the summer of 2007 and is now being used by college students,frat brothers and perverts up and down the east coast!

2.Nice Big round mound of butt that defies the laws of physics.

1.Jimmy have you seen "Billy Duff"? (while pointing out a target)
2.I was strolling down the beach earlier and saw a "Duff".
3. "Duff" to the right!
4. That's quite a large "duff".

by Joemy mckenzanela November 16, 2010