The point at which the drugs kick in, usually after taking amphetamines, halluciogens or substances such as MDMA (ecstascy).
Mate, I was coming up on those pills well hard!
by uphoriak April 13, 2005
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Slang for a plan to steal as much money as possible from somebody to avoid being on the street straight out of prison.
I’ll be coming up good and fast as soon as I get out, it’s sheer genius and it’s all mapped out to perfection.
by Dr Bunnygirl February 25, 2019
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somethin that's not quite happenin yet, but on the vurge of blowin up or makin some serious noise.
I got some thangs in the works but I can't talk about it yet. It's definitely on the come up, word ta mother.
by the excalibur November 7, 2006
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Used to define something clutch or a great opportunity. Can be used to describe a positive outcome to a situation. Usually used in reference towards commotitties or women.
"I just got these new yeezys on aliexpress for $5 bruh" "Bro that's not a come up you trippin ass nigga"

"I just copped me some percocet this is the biggest come up ever"
by xiexiexiaopunyo69 May 3, 2017
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on the track to mastering a skill or trade.
"yo that dude is nasty! he's about to hit is big huh?"
"yeah, he's on the come up."
by derek "malik" ban February 12, 2008
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A bargain, or a found item that is of value to the finder.
"One man's trash, that's another man's come up." - from Thrift Shop by Macklemore
by amrcn_werewolf September 13, 2012
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to steal some shit and sound like a badass
Badass: lmao dude, i have come up on a ton of lollipops from the barber!
person:holy fuck
by faggotskillgays December 7, 2016
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