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synaptically challenged

Describing someone of less than optimal cerebral functioning.
Is it me or is our waiter a little synaptically challenged?
by CWil December 14, 2010
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spacially challenged

someone who cannot for the life of them tell what fits where
Damn that leftover pasta didn't fit in that box." "Well, duh! You're spacially challenged!
by ahoad June 14, 2011
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orgasmically challenged

I was fucking some girl last night... but she's orgasmically challenged
by carz January 5, 2007
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fecally challenged

Doug has been fecally challenged ever since he started taking his psych meds.
by frenchie 312 December 23, 2015
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Horizontally Challenged

When you’re an edgy, fresh out of uni, 500 pound, buzzfeed reading History teacher.
ME : Go to the gym you fat fuck, also why do you own a Mini?
HIM : IM HORIZONTALLY CHALLENEGED YOU WEIGHT SUPREMICIST FATPHOBIC ASSHOLE

Horizontally Challenged
by Socialist Canadia October 17, 2018
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directionally challenged

A colloquial, quasi-humorous term for someone who is unsure of their location in space and may even be unclear about the left versus right sides of their own body. As psychological testing suggests, women may tend on average to have better liguistic skills than men, while men, in general, might have better orientation in space, so a man who is "directionally challenged" may be seen as less masculine by his peers. If a lifelong trait, it may represent a form of Minimal Brain Damage (MBD) related to Dyslexia or Attention Deficit Disorder (ADD); but if it occurs for the first time in a middle-aged or older person, it might herald a future dementia, such as Alzheimer's Disease (AD).
One reason (aside from instilling discipline) that the armed forces emphasize close-order drill in the training of recruits is to weed out the directionally challenged as someone who is such--"S'matter? Doncha know yer left from yer right? You directionally challenged or sompin'?"--will tend to do poorly on the battlefield and may even jeopardize the lives of his or her fellow soldiers, sailors, or fellow fliers.
by DrWhosis April 3, 2010
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reality challenged

A blanket term for "birthers", "truthers" or "deathers" Reality is too uncomfortable for them, so they start to believe in strange conspiracies.
I can't believe that he thinks that Osama Bin Laden is still alive. He's definitely reality challenged
by Mr_Ectomy May 27, 2011
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