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short a couple chromosomes

idiom/adjective phrase: to be mentally deficient in a very noticeable manner.

Etymology:

From the fact that many cases of mental retardation involves having an abnormal number of chromosomes.

Notes:
Funnily enough, means the same thing as "to have a couple extra chromosomes". "To be short a couple chromosomes" is perhaps a more natural way of expressing the idea as it plays to the human intuition that "more is better" and also because it is very easy to imagine how someone without the normal number of chromosomes could turn out retarded; however, "to have a couple extra chromosomes" may actually be more accurate in most cases. The most common genetic cause for mental retardation is Down's syndrome, which actually involves having more chromosomes than the normal person (a third copy of chromosome 21, to be precise).
I asked Zoe why her cousin was such a manchild, and she said, "Oh, he's short a couple chromosomes."
by Choosy Floozy November 24, 2019
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Seminal Short Cake

When a short, robust woman is cream pied
Dude! Last night I turned my girl into a seminal short cake.
by Blossom_Shinagains September 21, 2019
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Eat My Shorts

Bart simpson's PG way of saying "Eat My Ass"
"eat my shorts!"
by AugustTheHornyInventor July 24, 2022
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Short Person Energy

Someone that while they may not physically be small, project a ‘small’ presence in a room, whether that be through looks, attitude, or actions. - Morgan
Person - “yo, you have short person energy”

Cate - “WHAT NO! I HAVE TALL PERSON ENERGY, I AM A NORMAL GAL, WITH A NORMAL HEIGHT”

Person - “nah.”

Cate - “:,(“
by NotCate...&Iwouldneverb June 9, 2020
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Short-Bus Renegade

A mentally handicapped person, often made fun of or mocked by others. popularized by an AIM buddy icon from www.ballericons.com
by SqUuUeezy June 7, 2003
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short man syndrome

The need for a person of small stature to own a large vehicle (an SUV or a truck).
She's definitely suffering from short man syndrome, she's barely 5 feet tall and she's driving a Hummer. Her eyes barely come above the wheel.
by xxlinneaxlovexx March 1, 2009
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STRAWBERRY SHORT-FACE

After a guy earns his Red-Wings the girl pulls some of her bloody pubes out and throws them in his face, yelling "Strawberry Short-Face!"
"Yeah so we're 69-ing and she's on her God Damn period! So I gave that slut a Dirty Lifeguard! But while I'm laughing at her, she totally Strawberry Short-Faced me, man!!!"
by 9078675309 October 15, 2008
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