Downsyndrome like in character. Used more as a nickname for someone who acts like they have an extra chromosome.
Sean didn’t notice that he voted for Biden instead of trump because he likes all the red buttons in the ballot booth. Downy strikes again. Nice job Downsyndrome Sean.
by Pleubodoen November 28, 2022

The Downie 500, used mostly in middle schools and high schools in America, refers to a group of three or more mentally and physically handicapped people using their electric scooters to get around school. Basically a term to call a group of retarded people who cannot use their legs traveling from place to place in large groups.
Oh shit looks like the Downie 500 is coming to town because look at all those tards chasing after their retard wrangler
by mamaswhorecollector September 4, 2019

by WeAllHateMason September 8, 2025

Down syndrome, also known as trisomy 21, is a disease with a connection between mental disability and physical malformation. A downie is a person with this condition.
by TheAlmightyDario April 6, 2020

Someone who has no plan in life of going anywhere, addicted to drugs, can’t go without weed and smells like shit, doesn’t shower and wears the same clothes day in and day out and has no potential to be worth anything.
by EAnigga May 24, 2022

A Downy is a person that is part of the syndrome of the down’s organization. This organization consists of many different honorable men and women with serious uncontrollable retardation. Not necessarily born with Down syndrome. Just someone who embraces the way. The Downys can also speak to each other in there own language.
by master doitch October 4, 2022
