(v) Refers to inflicting damage or violence; can be done by ruining a business, venture, stealing one's girlfriend, or in any upsetting or ruining one's life.
by Lambnesio September 17, 2008

Another way of saying that you were hooking up with a chick. Fooling around, scoring. It doesn't signify a specific act.
Last night I was pimpin' shit up with Tara but her husband came home so I had to run out the back door.
by whillscf September 8, 2009

Whenever something really turn you on, hooks you, intrigues or interests you, that thing "fucks your shit up." Only use for major things, not minor things; i.e., you wouldn't say "Cheetos fuck my shit up" unless they literally feel orgasmic in your mouth. And, yes, this idiom allows sarcasm. *Can be referred to as an acronym, FMSU.
Angelina Jolie fucks my shit up."/"Man, whenever I see a girl in a corset...whew! Fucks my shit up."/"Camaros fuck my shit up. They're so gnarly."/"Deftones. FMSU.
by Feral_Prodigy October 17, 2010

by emmanuelbellith February 18, 2009

Dude, I see two of everything... Pass me another beer I'm getting shit house fucked up and having sexual intercourse with the least attractive woman here. High five!!!
by Rusty Dalton August 24, 2008

by LMHSblowsmacock June 10, 2010

by SickAD June 10, 2009
