When you lift your hand to stop a perfectly good conversation of mocking somone. "Talk to the Hand" is, has, and always will be stupid stupid stupid. It is done by annoying white girls and oreos. Stupid Stupid Stupid.
Me: Wow so I heard your an idiot Stupid idiot: Talk to the hand
Me: Wow stupid!
for example:
1:hey cutie
2:sorry I don't know you... I'm not talking to strangers..
1: c'mon cutie... talk to me...
2:talk to the hand!! *leaves*
1:tch..whatever *leaves*
something like that