Ghetto Bootie Share definition Flag A very eye catching bump on the rear of a female, can be slapped or humped for pleasure. Damn! Gabby has one big ghetto bootie. I wanna slap it soo bad! Ghetto Bootie by Shawn September 25, 2004 0 0 Get merch Get the Ghetto Bootie mug. Buy Now — $32.95 See more merch