A sexual practice that involves inserting your fist into the partner's anal cavity and thereby influencing the control they have over moving their dick.
"I tried Muppetting with my girlfriend last night, it was funny seeing how I could make her dick move around."
When a human being is so out of control it is as if they are being controlled by a muppet. (The implication is that the human has a muppet's hand up his or her ass, controlling his or her every move.)
Man, Doug is whacked out; he's singing nursery rhymes! That's some muppetic irony shit right there!
A rare genetic defect that can affect anything from frogs to pigs to even people. It turns the individual's skin into a felt-like substance and causes them to sing randomly. Most people infected with the gene are forced to live on Sesame Street, where documentaries are frequently shot to show their lives.