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simp-mania 

The entire fucking pokemane chat. This term may also be used on other popular e-girl streamers which are similar to pokemane, in which 30 year old men who live in their moms basement donate 2000 dollars to, in order to get attention from thoust female streamer those type of people are attracted to. If your reading this past 2020, you could find much more information on the word simp on other websites, for example wikipedia.org
*logs on to twitch*
*sees pokemane live*
dam thats gotta be simp-mania over there holy shit
simp-mania by Smokyoin October 16, 2020

Period Mania 

The scientifically proven phenomenon where women, who live and spend time together frequently, develop similar menstrual cycles as each other. The cause is yet to be determined.
Those girls are so close, I hear they have period mania.
Period Mania by FIFA Overlord March 10, 2016

mask mania 

An affliction causing the sufferer to worship face masks. The afflicted live in constant fear of illnesses, and of those not wearing masks.
"Hey man, did you talk to Steve this weekend?"
"No, im avoiding him. His wife suffers from mask mania, and will go absolutely nuts if you dont wear one."

trash mania 

A statement that describes sometehing that was said that was ignorant, stupid or just plain dumb. Orginated in Brooklyn Center, MN.
Boy 1: Is it true black people all like rap?
Boy 2: Dude, you on that trash mania!
trash mania by Michael Hannah March 14, 2006

grundle mania

festivity of playing with the grundle
hey sara, you going to grundle mania this weekend? it's gonna be a great time. Don't worry nothing will be tainted
grundle mania by steve mofo December 6, 2006

Paxil mania

One of the side effects of the anti-depression drug Paxil is the onset of a mania state, the opposite of a depressed state. Instead of low energy levels, someone experiencing Paxil mania has an excess of energy.

Dangers include making unnecessarily hasty decisions with possible terrible unseen consequences, confronting others (and sometimes getting into fights with them), excessive spending on sometimes questionable items.

Somebody with Paxil mania is more likely to lose their job, lose their significant other, lose their house or apartment, or lose something else of value.

Paxil mania almost always ends with a crash, that is, a return to deep depression from a state of apparent happiness. The crash is often accompioned by an interaction with a mental health hospital.
John checked into a mental hospital after he crashed from his Paxil mania.
Paxil mania by tokugawa227 September 1, 2011