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Rapper Knock-Out 

The title of the boxing video game that is featured in the music video for 50 Cent's Piggy Bank. This imaginary video game features 50 Cent as the best and strongest boxer, who takes on all of his real-life enemies in the boxing ring. Those enemies appear symbolically, as maybe the producer of the video game wasn't able to make all of their faces in 3D. Among the rappers getting knocked out by 50 Cent are Jadakiss, Fat Joe, and Nas. Game is never in the ring with 50, but he is featured as a Mr. Potato Head. This, of course, led game to create the retaliatory song "Mr. Potato Head", featuring Phat Rat, which many consider knocks out Piggy Bank.
Dude 1: Hey dude, you wanna play a video game?
Dude 2: Not unless it's that boxing game from Piggy Bank.

Dude 1: Haha, Rapper Knock-Out. Who are you gonna be?
Dude 2: Foo! 50 Cent of course! I wanna win.
Rapper Knock-Out by Rodzilla November 2, 2005
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KO (KNOCK OUT) 

To get layed out cold with a very powerful punch
Mann youd get KO'd if you got in a fight wit me.
KO (KNOCK OUT) by hatabitchsmacka February 5, 2004

Knock Up Knock Out 

A woman so attractive you want to get pregnant to keep her.
The attractive level must surpass a desire to not have children. It will even override common sense however the woman must be a true beauty, not a decent one.
1. That Naomi Komaki is so hot I want to get her pregnant so she would have to stay with me. She's a real knock up knock out.
2. That knock up knock out is so hot I put a hole in the condom.

donkey punch knock out

When you are fucking a chick doggystyle, donkey punch yourself, knocking yourself out. Going for the double knockout, fall face first into the back of the chicks head knocking her out, while still inside her you both fall to the floor.
"Louis and Tara both have concussions from that donkey punch knock out they performed lastnight."

Cuban knock out 

When a male spreads semen upon his fist and punches the recipient in the face.
Cindy said, "I have a black eye because Bryan gave me a Cuban knock out."

Critical Knock-Out 

When you get KO'd by an attack that you should've survived, had it not landed a critical hit.
CKO for short.
Game: Enemy attacks!
Player: No worries, I can survive this.
Game: Critical hit!
You've been defeated...
Player: Ugh! I hate Critical Knock-Outs!

Louisiana Knock Out 

While your best babe is giving you a BJ while your standing up, and she's on her knees on the floor, you guzzle a bottle of red wine, then shotgun a beer. Right before you start puking all over her head, grab her by both ears so she can't back off. While your puking all over her head, force your meat stick down her throat until you blow your load and the gagging makes puke and nut shoot out of her mouth like a fire hose. Take your dong out her mouth and knee her as hard as you can on the chin.
My girl loves to suck my d*ck, but she talks to much and I had to get up early, so I gave her a Louisiana Knock Out.
Louisiana Knock Out by Lance Dirk January 1, 2022