Different uses:
To agnew, to have agnewed, to be an agnew, epic agnew
Sam: Remember that time me and you were in Mikes car and rolled up on that dude and that underaged girl making love?"
Oli: hahaha, we weren't afraid to hit people in the face Rob: hahahaha
Sam: Rob, you just pulled a total agnew
Spiro Agnew was VP under Nixon until resigning in the wake of a criminal indictment. After Nixon resigned due to Watergate, Agnew naturally became a follow on joke when someone used the word "Nixon" when referring to taking a shit or a bowel movement.