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Macduffed 

To be made a fool of; To make a fool of; To confound or prove wrong; embarrasing someone: Being embarrased.
A guy gets stuffed on the b-ball court.
Everyone yells at him, "Macduffed!"
Macduffed by James H. McArthur February 11, 2007

Madoffed 

To be scammed in a financial, or Ponzi scheme. Money lost is often several millions of dollars.
Steve: You hear about that cheesedick on Wall street that suckered everyone into giving him money, then ran off on his Yacht?

Charles: Yeah, they got Madoffed.
Madoffed by Client 09 January 9, 2009

MacDuff's 

An exorbitantly over-priced shit hole of a restaurant located on the corner of 4th and Pine St. in Jamestown NY. Owned by a pompous, senile, and downright unpleasant crazed man affected by severe PTSD, MacDuff's is infamous for catering to approximately 50 gullible, senile, and rich old people annually, as well as being one of the greater rip-offs in the western hemisphere. No one likes the place, except those whose brains have become victim to severe atrophy and are lured into the establishment by the aforementioned owner's domineering demeanor. MacDuff's is one of those places that would be better off not existing, along with the assface of an owner.
Hey, what smells like rotten fish, death, cold cream, and napalm???

Oh, it's only MacDuff's. You get used to it after a while.
MacDuff's by 3rd St. Cowboy May 25, 2010
One of the most important characters in William Shakespeare's Macbeth. In the play, he is the Thane of Fife, starting off as an incredibly minor character. However, after Macbeth becomes king of Scotland, he orders Macduff's family to be killed, Macduff swears revenge. It was prophecized that Macbeth could nto be killed by one born of woman, but Macduff's mother had a Caeserian Section, so he techinically wasn't born, he was taken out. Macduff decapitates the tyrant and holds his head aloft for all to see.
"Know thee Macduff was from his mother's womb untimely ripped!"
Macduff by Hydragon September 4, 2005

madoffed 

Have your parents been madoffed?
madoffed by lol omg January 8, 2009
A shitty fishing port on the Moray coast in Scotland populated by smackheads and psychos, mostly.
I'd rather eat my own tampons than live in Macduff.
Macduff by EmpressOfBlandings September 22, 2005