Bubons 

Slang Jon Stewart often uses for the flu or common cold.

Based on the way he pronounces it (tongue-in-cheek Godfather character accent) it's probably the plural form of the Italian word 'bubbone,' a swollen lymph node characteristic of bubonic plague. It probably developed as slang for an infection because bubonic plague is so infectious. Stewart probably picked it up growing up in the NJ/NY area.

"I have the bubons again. It's the second time in three months. Let me say this to anybody out there with children at home: buy an autoclave."

Jon Stewart
The Daily Show
February 22, 2011

Bubons by TDSFan123 March 12, 2011

bubons 

noun, a severe cold or flu that's kicking your ass, usually caught from kids who bring it home from pre-school.

Made famous by Jon Stewart on The Daily Show.

"Did you see the Daily Show last night? Jon Stewart had the bubons, he could barely interview that guy."

"I can't go out for drinks, I've got the bubons."

bubons by zen velo March 18, 2011

Bubonic Plague 

Bubonic Plague is a contagious, often fatal epidemic disease which killed a third (50 Millon) of the world's population of Europeans and Asians in the 1430's. The bubonic plague is caused by the bacterium Yersinia pestis, transmitted from person to person, a bite of a flea from an infected host, and a bite from an infected rat.It is characterized by chills, fever, vomiting, bloody semen, diarrhea, the formation of buboes, inflamed lymph nodes (around armpits, neck, and groin), pain areas in the abdomen or muscles, coughing blood, the whole body would feel fever, chills, fatigue, or malaise, Gastrointestinal (nausea, vomiting, and diarrhea), and commonly, bleeding, delirium, headache, phlegm, shortness of breath, or swollen and tender lymph node.

The Bubonic Plague is a virus

Bubonic Plague by TF2 Fan April 1, 2017

bubonic chronic 

1. weed that gets you straight FUCKED UP

2. Very potent marijuana

Yo Collins used to sell that fuckin bubonic chronic, damn shame the po blew up his spot.

bubonic chronic by ABJ March 20, 2005

bubonic plague 

A contagious, often fatal epidemic disease which lolwtfpwnd a third of the world's population. The bubonic plague is caused by the bacterium Yersinia pestis, transmitted from person to person or by the bite of fleas from an infected host, especially a rat, and characterized by chills, fever, vomiting, bloody semen, diarrhea, and the formation of buboes.

Me: I have the bubonic plague. My lymph nodes R hurt.
Onlooker: You are lolwtfpwnd.

bubonic plague by sux0r May 11, 2006

Bubonic Vag 

That stinky infect pussy your girl has, that one when you go down on her you have to burn your tongue afterwards. Just a gross stinky vagina.

Bro i was totally going down on her and it tasted like straight ass and not the good kind. That bitch had a serious Bubonic Vag

Bubonic Vag by black jesus4356 January 11, 2017

bubonic 

good marijuana.

"I got some bubonic product and then we chilled for a bit." -Snoop Dog

bubonic by Laura February 21, 2004