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Name for the worst people in existence, also name for vagina or something thats broken.
Duff: "My name is @##$ Duffus"
Bystandard: "How do you sleep at night"
duffus by Patrick!@#$%%^^ April 28, 2006
A long, thick, uncircumcised penis; The best sex any member of the female species could hope for.
That guy had quite the duffus!

I had some duffus last night..... it was phenomenal!
Duffus by imsothug May 22, 2011
To absolutely fucking murk a mans with your bare mitts.
Mi yute I’m bouta straight duffus this mandem ahlieeee.
Duffus by Macdaddy93 June 28, 2018

duffus fuck 

a duffus fuck is a fella who is a complete dumb shit in life and don't know how to react to being called duffus fuck
duffus fuck by duffusfuck April 14, 2017

muffus duffus 

Get over here and clean up your mess, muffus duffus!
muffus duffus by ONPS January 30, 2008

Rufus Poofus Mc.Duffus 

This is a girl or boy who fakes his LGBTQ identity to get into sleepovers of the opposite sex and perv on them.
Person A:Did you here about that time Jamal lied about being gay to get into Vicky’s sleepover?

Person B: OMG what a Rufus Poofus Mc.duffus