When somebody is being an pain in the arse and preventing you from doing something you are trying to get done. This expression is used as an annoyed slang response when this situation occurs.
To respond in an equally flirty manner to somebody's attempt at steering the conversation in a flirty direction.
My tennis partner remarked that I was "good at handling balls" and then winked. I wasn't sure whether to flirtciprocate or not so I just said "too right!" and laughed awkwardly.