Used to ask an indiviudal how things are going. Can be responded to in urban settings by using the word Chillin or in Jamaica by saying Cool
A- Yo man what's up?

B- Chilllin
by ICO777 August 12, 2009
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term used when you did something badass
after slapping a bitch thats "whats up"

klucthing it
by benjijuice18 July 27, 2009
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A question about what another has his attention on. What is he thinking about or busy with? "Up" in this usage is referring to a slag from around the 1930s meaning: occupied with or busy with.
When I saw him he was angry so I asked "what's up?". But he would not tell me what he was angry about.
by Scottmana September 15, 2007
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WHAT'S UP! is just a greeting not a question not asking anything just an aknowledgement/ greeting in passing and the only reply in that tone , you have to listen for the tone, is what's! up and keep it moving. Important listen for the tone.
walking down the street and see someone, eyes meet you both have things to do or nothing to do whatever the case you say, what's up! and you keep it moving. don't just say this in any situation you have to use your senses if you don't have any senses don't try it because if you aint feeling it or you convey it in the wrong way it could be misinscrewed in the wrong way that same what's up? could be a challange or a question in which case if you can't reach for your feelings or senses just say hi, that nuetralizes anything other then the greeting.
by "COODIE" DOG April 19, 2010
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Something you say to someone who looks sad or troubled
Hey whats up, u don't look like your happy self
by 20104u January 15, 2010
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