twizzle smacked Share definition Flag the piont of being so shit faced drunk and/or high that you have no rememberance of any events of the night. damn i was so twizzle smacked last night. twizzle smacked by girlgonewild4444 November 7, 2009 0 0 Get merch Get the twizzle smacked mug. Buy Now — $32.95 See more merch