Similar to No Nut November, a challenge where you may not intentionally ejaculate or orgasm under any circumstances. The challenge takes place from midnight on 1 Jan 2021 to 31 Dec 2021 at 11:59 PM.

Wet dreams and pre cum are permissable. You can watch pornography, masturbate, or even have sex (although none of these are recommended) as long as you do not orgasm.
"You doing No Nut November this year?"
"Nah, I'm waiting for No Nut Twenty-one"
by Jack Goff 02 November 3, 2020
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Two guys named Tyler Joesph and Josh Dun that made the best band on earth and like to except grammys with no pants on 😂
by |-/ is life February 21, 2017
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2 guys with annoying fans, but great complex music. They go wild at their concerts and are genuine people that just enjoy what they do.
wow did u see the twenty one pilots concert they did crazy shit
by heyheyok6 October 29, 2018
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One of the best musical duos ever to live. If you haven't listened to their music then, you are really missing out. And if you don't like them, you have awful tastes in music.
My friend: "Your obsession with Twenty One Pilots, is getting weird."
Me: "Leave now."
by loyal top fan August 1, 2018
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A group that is so addicted to twenty one pilots, that they need it like its crack.
Omg, they listen to every song of theirs, they are such twenty one crackheads!
by Tyler dun September 1, 2016
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Twenty-one backtick is how you say the text " 21` " which is typed by hitting the three top-left keys from right to left on a standard English Keyboard: 2, 1, and backtick
Used in IM to mean over and out.
Guy 1: OK, I'll see you in like 5 minutes
Guy 2: k, 21` twenty-one backtick
by Nizzity June 28, 2007
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A good band that will make ur bones shiver like a skeleton when they eat ice cubes... aka they make you quake
My friend was listening to twenty one pilots and he queeved in my bed and made a big brown mark
by Jsjdifof January 27, 2019
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