when you've been up for forever on meth and are starting to trip
hardcore - ie, when your face is beginning to become
one giant open bleeding sore from picking at it.
"damn, i am so
twacked out, i plucked until i dont have any eyebrows left."
"your pupils are so big you dont have any color in them - you're hella twacked out."
"for the last time, that is a
MINIVAN, not the
FBI - quit getting so damned twacked out!"