The combination of Totes (totally) plus McGotes (roughly meaning to agree), yielding a phrase with the meaning to "totally agree" with someone, but in a cooler and strangerway. Also can mean that you agree with an activity, as in "I agree" or "I'm in" as a loose use of totally agree.
Eve: I'm going to go chow down on that apple the snake told us about, are you in?
Adam: Totes McGotes! I'm way down for that! Let's go!
A rhyme negation of the slang totes (meaning totally) this phrase is used as a correction and is followed by the 'better' descriptive (following the pattern of all rhyme -negations)
In the classic tv commercial:
Girl 1: "He's totes adorbs"
Girl 2: "totes magotes, he's cray-cray amaze"
(this follows the standard pattern for rhyming negation:
Friend 1: "What should I wear? It has to be conservative"
Friend 2: "conservative shmervative, go wild!")
note: In the full commercial, the follow up comment of "totes magotes" is used incorrectly.
12 step recovery jargon referring to someone new who talks about how great life is, now that they're sober. Usually meaning that the person is out of touch with reality.
The new guy seems pretty happy for a dude who has no job, no money and no family. He must be on a pink cloud.