tapping a vein Share definition Flag Injecting drugs into your bloodstream. Usually done by only the most hardcore addicts, as it results in the quickest high. "I know this junkie that got HIV, from tapping a vein." tapping a vein by D. Gould February 14, 2006 0 0 Get merch Get the tapping a vein mug. Buy Now — $32.95 See more merch