Serodonic 

A state of extreme lethargy after taking a substantial amount of seroquel and trazodone in combination.

I can’t get up right now, I’m in a serodonic state.

Serodonic by BertBastard October 16, 2020

Sardonicast 

A group consisting of three or more gay men all from differing nationalities.

I went to the beach today and noticed a sardonicast loudly expressing their thoughts of film and television.

Sardonicast by SpencerNolanRice May 16, 2018

serotonin donor 

Someone people turn to when they're sad who makes them feel better.

Dude, I was so unhappy about my girl, until I spoke to my serotonin donor who really helped me feel better

serotonin donor by jonfurstn1 November 27, 2009

Serotonin

A neurotransmitter believed to regulate mood. SSRI's inhibit the reuptake of serotonin in the brain (leading there to be more serotonin left as a result), hopefully improving the mood.

Personally, a good blast on the Codeine cheers me up more than any SSRI.
Perhaps it's my endorphine system rather than my serotoninergic system that is fucked.

A lack of Serotonin is believed to be a cause of depression. It also controls appetite, among other things.

Antidepressants often (through various mechanisms) increase the amount of serotonin in the brain.

MDMA (Ecstacy) causes a massive (cascading) release of serotonin in the brain - responsible for both it's euphoric effects, and the depressive aftereffects (less serotonin remains in the brain, until generated again)

Serotonin by heterocodeine December 20, 2008

serotonin sucker 

Someone who is so miserable they bring you down and sap your happiness.

Everytime I'm with that serotonin sucker brother of mine, I feel gloomy.

serotonin sucker by Jonfurstn November 25, 2009

Sardonicast 

A podcast with three cynical assholes that talk about movies and other dumb shit. A Brit, a gay Canadian and a failed abortion are our stunningly critical hosts.

Him: I love Sardonicast its my favorite podcast!
Her: Ohh he must be gay

Sardonicast by Yourfriendisgay May 5, 2018

Seronich 

Famous twitch streamer known for pigs, outstanding bedwars plays and anarchy.... wait a second

Is that famous Twitch streamer Seronich?

Seronich by demurei June 6, 2021