sepsisface Share definition Flag The politically correct term for a male "butterface." Everything looks good on him, 'xepts his (sepsis) face. Becky, look at those abs! Too bad he's got a bad case of sepsisface! sepsisface by kitty_bee April 24, 2010 0 0 Get merch Get the sepsisface mug. Buy Now — $32.95 See more merch