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The act of to pulling your underpants out of your ass crack or fixing yourself after being the recipient of a wedgie.
I named this tight leopard print thong "Master" because it keeps me picking cotton all day.
by Dick Thimble October 18, 2010
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4
When male/female picks dried cum out of male pubic hair, either with teeth or hands.
Person #1--Hey, what did you do last Wednesday?
Person #2 -- My girl was picking cotton.
by Decafpancakes December 02, 2016
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6
the act of being rediculously drunk; the remaining moments of conciousness before passing out
Friend "Hey, are you drunk?!"
You "Nahhh, I was drunk an hour ago. Now I'm picking cotton"

by Frederikson c304 January 29, 2006
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7
When you jerk off a black guy and he ejaculates, and you have to pick out semen from underneath your fingernails.
"I was picking cotton after a fun night with Bill Cosby"
via giphy
by Valterain November 19, 2016
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