When a person, a girl in particular, is contemplating whether or not they want to lose their virginity. Typically these people appear to be the most wholesome of people. Dont be fooled. These people are what you would call closet freaks. And more often than not take what they feel is theirs, i.e. the male body, and think nothing of it.
Catholic school girls are typically on the brink, if they havent done it already
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.