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It means the first thing that comes to your mind(usually along the lines of sex, alchol, drugs, weed, etc) It should be used when you want to do a combination of the previous things listed or if you want to do anything that will entertain.
Yo Lets get laddered tonight!
Dude I'm so laddered right now.
Yo I laddered that chick last night she was awesome.
Yo I got weed in my car wana go get laddered?
by midevilworm December 04, 2010
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