a "pandemic" that is used by boys as an exuse to hold a girl's hand. Very effective. The only known cure is to hold the girls hand and apply pressure. You must also give the girl a hug after letting go of her hand.
Linus: OMG!!!
Taylor: What?
Linus: You have Knuckleitis!
Taylor: oh no!
Linus: Ill save you! now give me your hand.
Taylor: What?
Linus: You have Knuckleitis!
Taylor: oh no!
Linus: Ill save you! now give me your hand.
by Trevor3657 February 11, 2009
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noun. Short for "nuckle tattoos," or small tattoos that appear across the knuckles. Usually a series of small tattoos near a person's nuckles that when put together (ie. a fist is made and two hands are placed next to each other) form a complete message. Typically one letter on each finger and not the thumbs.
That nerd tried to be all cool with his lame "DONTPANC" knucktat. He should have gone for something better, like "SAND" on right hand and "WICH" on left hand. You know, as in a knuckle sandwich.
by PJeigh February 8, 2006
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by larryt david November 29, 2007
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