giggleshmirts Share definition Flag When someone has to shit and they laugh so hard a little bit comes out. Likely to happen when the person has diarrhea. Will: Has anyone seen Andrea? Rob: She went to the bathroom. She has a bad case of giggleshmirts. giggleshmirts by C. Epic July 22, 2011 0 0 Get merch Get the giggleshmirts mug. Buy Now — $32.95 See more merch