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gameover 

When you have a really long gaming session and the next day you eyes hurt and you have a massive headache.
Paul: Yo Carl, how come you couldn't show up for work today?

Carl:I had a massive gameover last night from playing Modern Warfare 2 too much.
gameover by truegamer88 November 21, 2009

Gameover 

The hangover like tired behavior seen from teenagers who stay up late playing video games and drinking caffeine.
-Hey dude, good job playing Call of Duty last night
-Yea we were up to like 4, and i had a total gameover when i woke up.

gameover 

the aftermath of staying up all night playing video games,with symptoms of a hangover the next morning.
i stayed up all night playing uncharted 2,and went to bed at 6 a.m. woke up at 2 with a gameover.
gameover by ronda howard January 8, 2010

Gameover 

The hellish headache after playing 7+ hours of video games.
1: Dude, I have the worst gameover.
2: Oh damn, how?
1: I beat Dead Space 2 on Zealot overnight.

2: Jesus bro, thats hardcore.
Gameover by OrnateCocoapuff February 22, 2011

Gameover 

(noun) The induced state of worthlessness, sore body (and bottom), incompetence and general increase of mental and bodily retardation.
Other side effects may include headaches, hunger and thirst, prolonged procrastination, impudence, and poor management for the remainder (if it exists) of one's time.
Ahh, you have a Gameover.
Gameover by Live By Experience March 28, 2011

Gameover 

After I fucked that bitch I put gameover all over her face.
Gameover by Huff-DCP July 2, 2004