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Cut-throat Bitch 

A person (usually a female) who is cruel and does not care about another person's feelings. S/he can excessively rude or obnoxious and or extremely competitive (hence the word: cutthroat).
Kutner: "Cut-throat Bitch" is your official title.
Amber: It's a game. You can either play for fun or play to win. If you want to win, you want cutthroat.
Cut-throat Bitch by John Doe 186 January 18, 2009
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cut-throat bitch 

A nickname given to Amber (Anne Dudek) by Kutner on the hit FOX drama House MD.
Kutner: "Cut-throat Bitch" is your official title.
Amber: It's a game. You can either play for fun or play to win. If you want to win, you want cutthroat.
cut-throat bitch by M.G.T. December 8, 2007