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Slang, noun.

Crank” is slang for a low purity, crystallized Methamphetamine that is administered in a powder form. Crank, like all other Methamphetamines, is a stimulant that acts on the central nervous system to increase heart rate and alertness of its users. Highs on the drug last between 8 and 24 hours, and often include a violent "crash" period where the user tends to be prone to aggression. The drug received the nickname “crank” because it was often smuggled in the crank cases of vehicles.

Methamphetamine is taken orally or intranasally (snorting the powder), by intravenous injection, and by smoking. A common misconception among users is that some administration methods are safer than others, while in reality all act on the body the same exact way. Methamphetamines damage nerve endings, which cause naturally occurring neurotransmitters—Dopamine and Serotonin—to be ineffective. Because Dopamine and Serotonin are responsible for easing pain (like the pain which comes from drug withdrawal), withdrawal periods are extremely painful because the body does not have its natural pain reliever to administer.

Methamphetamine withdrawal is said to be one of the most painful experiences a human being can endure, and users of the drug should should consider other safer recreational drugs.
Billy started doing crank because he was looking for the ultimate high and did not care about the consequences.
by Stephen Wood July 04, 2005
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2
someone who is a bit of a twat or annoying you
"shut up you crank"
" your boyfrind is a fucking crank"
by jogonjon February 12, 2009
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3
A cheap form of meth made in trailer kitchens. often causes gritting of teeth, assholeyness, destruction, inability to pay bills, romantic relationships with ones aids infected cousin, and finally complete retardation.
1. Grary nd' nikole loves they crank.

2. The more CRNK I snort the mores i become the hulk.
by the magical muffin September 11, 2004
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4
to turn the volume of your sound system up real loud
"I love to crank up Metallica and watch the furniture fall apart!"
by Paulie January 07, 2004
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5
to cry and wank. after one has encountered an unfortunate incident in which they are forced to cry they go away to wank and cry at the same time.
jeremy cranked after ashley smacked him
by ziboi October 18, 2008
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6
n. a crazy person, especially someone who purports to be a scientist or inventor who has discovered the answer to some important problem facing mankind, like curing all diseases, unlimited energy, levitation, aliens, etc.

He defends his claims with the most ridiculous pseudoscientific crankisms, and claims that the government/mainstream science/experts are suppressing the truth.
Sometimes cranks are businesspeople, selling such wares as Q-ray bracelets that align your chi using q ions to give you enhanced energy.

Probably the best known internet crank is Gene Ray, for his Time Cube site.
by Khashishi May 29, 2010
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7
A female that display a number of the following characteristics: clingy, overly keen, smothering, controlling, easily stressed, highly opinionated, violent, emotionally volatile, unreasonable or just generally high maintenance.
1. "That girl i met the other week, bit of crank. she wont leave me alone!"

2. "I would come out mate but my girlfriends being a bit of crank about it"

3. "Stop being so fucking cranky"
by eagles85 July 10, 2008
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