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Clinical Depression 

clin-i-cal de-pres-sion
/klin-i-kal dih-presh-un/

A mental health disorder characterized by persistently depressed mood or loss of interest in activities, causing significant impairment in daily life.
Rosita has clinical depression. That is why she never wants to join family events.
Clinical Depression by kaosmoker September 30, 2018

Clinical Homies 

When two or more people have been diagnosed as being absolute homies
Me and my boy boner are CLINICAL HOMIES... more boys more boys!

Clinical Handshake

when a man/woman walks into a medical clinic, hospital, or nursing home and uses a comatose patient's hand to masturbate.
The best orgasm can be achieved through a Clinical Handshake.

clinical, hand, shake, clinic

clinically proven 

Clinically proven may mean virtually anything... including nothing. A "clinically proven" statement in advertising is an effective sales pitch, usually a vague claim that requires no hard evidence and isn't easy to disprove. As long as the mandatory "These statements have not been evaluated by the FDA (...)" disclaimer is on the label, it's not necessary to have competent and reliable scientific evidence to back it up.
When used along a sensible diet and exercise program, our new eggplant extract is clinically proven to promote weight loss!
clinically proven by Flixxx December 27, 2007

Clinical depression 

Also referred to as major depressive disorder, major depression, unipolar disorder or simply depression, this illness is a psychiatric condition marked by severe feelings of despondency and dejection, typically accompanied by changes in eating and sleeping habits, anhedonia (loss of interest), fatigue, somatic pain and, at the extreme, suicide ideation. Also occurs in bipolar disorder (depressed phase).
Clinical depression is a serious mental illness and quite different to the ordinary sadness we all experience from time to time.
Clinical depression by Doc_B April 14, 2015

clinically significant other

A significant other defined by an (undesired) medical condition, not by a agreed-upon relationship status.

Combination of "clinically significant" and "significant other."
They were only dating casually, but when he gave her the Clap, he became her clinically significant other.