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Short for "cisgender" (opposite of "transgender"), used to describe someone whose gender identity matches their anatomical gender at birth.

Occasionally used derogatorily.
Mark: I heard that Stacy decided to start her transition.

David: Huh? Dude, Stacy is cis. You mean her sister.
by Jfdadff June 29, 2009
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Short for cis-gendered, meaning someone who identifies with the sex they were born as. Typically used by whiny tumblr users who complain about not being accepted for who they are and yet bash these "cis" people for being born and being okay with the sex they were born with.
I am a female to male transgender and I hate white straight cis men.
by faultyfatality January 02, 2015
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Short for cisgendered; referring to someone who identifies with the gender they were assigned at birth.
The opposite of Transgender would be Cisgender .
by Patchesthepirate March 12, 2017
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Commonwealth of Independent States; putative successor to the USSR, except that the Baltic Republics of Estonia, Latvia, and Lithuania never joined. Contrary to another definition of CIS at the Urban Dictionary, the CIS does not stand for "Communist Independent States." Moreover, that definition has the CIS existing BEFORE 1991, and includes Kazakhstan as "not officially part of the Soviet Union." Kazakhstan was, in fact, one of the 15 republics of the USSR until 1991.

The CIS came into being December 1991. Mostly consists of regularly scheduled conferences of foreign ministers and defense ministers.

In 1995, members Belarus and Russia created the Commonwealth of Sovereign Republics (CSR).
The August 2008 war between Georgia and Russia was unique in being a direct war between CIS member states, although there have been others waged by proxy.
by Killa Klown is wrong June 16, 2010
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Abbreviation for the Confederacy of Independant Systems. Second worst faction in the Star Wars universe beaten only by the wretched Alliance to Restore the Republic/New Republic as THE worst.
Seperatist movement! Ha! The seperatists are just a bunch of disgruntled corporate moguls who don't want their businesses infringed upon.
by Exor January 10, 2005
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Loud and obnoxious transgender people use it so they can deny the fact that they're not normal.
1. Omg what a cissy
2. Die cis scum
by Schmeckledorf October 07, 2015
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CIS is an abbreviation for the term "Collective Information Source".

A collective information source is an educational resource with information specific to a certain subject; it is usually held in a binder or folder.

A CIS can be created for general educational purposes, as a place to gather ones arguments during a disagreement, or out of pettiness.

This abbreviation is not to be confused with any of the following:
Cisgender, The Center for Immigration Studies, The Commonwealth of Independent States, The Council of International Schools, The Center for Internet Security, Canadian Interuniversity Sport, The Corpus Inscriptionum Semiticarum, Carcinoma in situ, The Center for Comparative and International Studies, The Knabenchor collegium iuvenum Stuttgart, a continuous ink system, a copper indium selenide solar cell, a contact image sensor, The Confederacy of Independent Systems, the towns in Italy and Poland, the mathematical function, the Cis beetle, cis regulatory elements, cis isotope alkenes, cisalpine, and the C# music note.
She disagreed with him so much that she created a CIS to give to him.
by PettyCrocker June 28, 2016
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