chu-chu Share definition Flag dirty, nasty, not good, gross Used in Southern Louisiana to explain to children what is not good. A little boy drops his lolli-pop in the dirt and picks it up to put in his mouth. His Uncle says, "Don't put that in your mouth, it's chu-chu." chu-chu by Jessie and Adam July 25, 2006 0 0 Get merch Get the chu-chu mug. Buy Now — $32.95 See more merch