This disease also known as Great Hall Food Syndrome, can cause severe nausea and weight loss. It is only contracted by eating food from the Great Hall at Duke TiP West Campus. Three weeks of a Bifidus irregularis infection can result in weight loss exceeding 20lbs. People who survive their encounter with Bifidus irregularis are known to be able to eat almost anything.
Fat Kid: "How did you lose 45 pounds in only 3 weeks?!?!?"
(Now) Skinny Kid: "I caught a severe case of Bifidus irregularis."
Fat Kid: "Westfood, huh? How many other places is McDonalds considered fine dining?"
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.