ayñomio Share definition Flag An expression in Spanish to indicate something is cute or denotes cuteness. It is short for "Ay Dios mío". That puppy is so cute, ayñomio.He said he loves me, ayñomio. ayñomio by TheJuha October 3, 2019 0 0 Get merch Get the ayñomio mug. Buy Now — $32.95 See more merch